Journal of Medicinal Chemistry p. 589 - 591 (1986)
Update date:2022-07-30
Topics:
Guzman, Angel
Yuste, Francisco
Toscano, Ruben A.
Young, John M.
Horn, Albert R. Van
Muchowski, Joseph M.
The (-)-S isomer of 5-benzoyl-1,2-dihydro-3H-pyrrolo<1,2-a>pyrrole-1-carboxylic acid (1) is about 60 times more potent than the (+)-R isomer in the carrageenan edema test and ca. 230 times more active than the (+)-R isomer in the mouse phenylquinone writhing assay.
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