6-Substituted 1,3,4,5-tetrahydrobenz[cd]indol-4-amines: Potent serotonin agonists

DOI: 10.1021/jm00117a013

Source and publish data:

Journal of Medicinal Chemistry p. 1746 - 1753 (1988)

Update date:2022-08-05

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Authors:

Flaugh Flaugh

Mullen Mullen

Fuller Fuller

Mason Mason

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Article abstract of DOI:10.1021/jm00117a013

A series of 6-substituted tricyclic ergoline partial structures has been synthesized and found to possess very strong serotonin agonist activity. A methoxy group at the 6-position greatly enhances activity, but at the expense of compound stability. Substi

Full text of DOI:10.1021/jm00117a013

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