Acrolein as a Synthon for 6-Hydroxytetrahydropyrimidines, 1,4(1,6)-Dihydropyrimidines, and Pyrimidines

Article abstract of DOI:10.1021/jo00391a047

A series of 6-hydroxytetrahydropyrimidines and 1,4(1,6)-dihydropyrimidines bearing a phenyl, methyl, or amino group at position 2, as well as the unsubstituted (parent) compounds of these families, were synthesized by reaction of acrolein with several ami