NEW PALLADIUM-CATALYZED ADDITION OF CYANOTRIMETHYLSILANE TO F-ALKYLATED 1-AZA-1,3-DIENES. A CONVENIENT ROUTE TO β,γ-UNSATURATED α-F-ALKYL-α-AMINO ACID PRECURSORS

Article abstract of DOI:10.1246/cl.1985.1387

2-F-Alkylated 1-aza-1,3-dienes, easily prepared from 1H-F-1-alkenephosphonates, smoothly underwent the addition of cyanotrimethylsilane in the presence of a catalitic amount of palladium(II) acetate or chloride to give β,γ-unsaturated α-F-alkyl-α-amino ni