AN EFFECTIVE METHOD FOR REMOVAL OF THE INTERNUCLEOTIDIC PHENYLTHIO GROUP FROM FULLY PROTECTED OLIGONUCLEOTIDES BY USE OF BIS(TRIBUTYLTIN) OXIDE

DOI: 10.1016/S0040-4039(00)98768-9

Source and publish data:

Tetrahedron Letters p. 4621 - 4624 (1985)

Update date:2022-08-04

Topics:

Authors:

Sekine, Mitsuo

Tanimura, Hiroshi

Hata, Tsujiaka

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Article abstract of DOI:10.1016/S0040-4039(00)98768-9

Several kinds of organotin compounds involving stannyl oximates have been examined as reagents for deblocking the internucleotidic phenylthio group from an appropriately protected S-phenyl diuridine phosphorothioate (1).Among them, bis(tributyltin) oxide was found to be very effective.

Full text of DOI:10.1016/S0040-4039(00)98768-9

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