Bioorganic and Medicinal Chemistry (2020)
Update date:2022-07-29
Topics: Synthesis Data Analysis Biological Assays Clinical Trials Literature Review Structure-Activity Relationship (SAR) Study Lead Optimization Toxicity and ADME Studies Market Launch Preclinical Testing Scale-Up Synthesis Synthesis Planning
Chen, Wenteng
Liu, Shuangrong
Liu, Xingyu
Pan, Youlu
Shao, Jiaan
The covalent binding nature of irreversible kinase inhibitors potentially increases the severity of “off-target” toxicity. Based on our continual strategy of chemically tuning the Michael addition acceptors, herein, we further explore the relationship amo
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Doi:10.1016/j.tet.2005.11.082
(2006)Doi:10.1134/S1070363207050210
(2007)Doi:10.1039/c39860000037
(1986)Doi:10.1021/acsinfecdis.7b00130
(2018)Doi:10.1016/j.tetlet.2008.02.064
(2008)Doi:10.1080/00397910008087049
(2000)