Preclinical Testing

Synthesis Medicinal chemistry Kinetic studies Optimization Data Analysis Structure-Activity Relationship (SAR) Analysis Ligand Design Purification and characterization Chemical Synthesis Biological Assays Structure-Activity Relationship (SAR) Studies Clinical Trials High-Throughput Screening Clinical Development Literature Review Structure-Activity Relationship (SAR) Study Lead Optimization Design Hit Identification FDA Approval Toxicity and ADME Studies Regulatory Approval Rational Drug Design Market Launch Structure-Activity Relationship (SAR) Pharmacokinetics Design and Synthesis Animal Models Lead Compound Identification Further Optimization Molecular Modeling and Computational Chemistry Biochemical Assays Toxicity and Specificity Testing Scale-Up Synthesis Pharmacokinetics and Pharmacodynamics Cell-Based Assays Toxicity and Selectivity Drug Discovery High-Throughput Screening (HTS) Target Selection Rationale Target Identification and Validation Post-Market Surveillance Pharmacokinetics and Toxicity Testing Target Identification Compound Screening Radiolabeling In Vitro Binding Studies Human Studies Future Research