Bioorganic and Medicinal Chemistry Letters p. 1502 - 1506 (2008)
Update date:2022-08-04
Topics:
Frechette, Sylvie
Leit, Silvana
Woo, Soon Hyung
Lapointe, Guillaume
Jeannotte, Guillaume
Moradei, Oscar
Paquin, Isabelle
Bouchain, Giliane
Raeppel, Stephane
Gaudette, Frederic
Zhou, Nancy
Vaisburg, Arkadii
Fournel, Marielle
Yan, Pu Theresa
Trachy-Bourget, Marie-Claude
Kalita, Ann
Robert, Marie-France
Lu, Aihua
Rahil, Jubrail
Robert MacLeod
Besterman, Jeffrey M.
Li, Zuomei
Delorme, Daniel
The synthesis and biological evaluation of a variety of 4-(heteroarylaminomethyl)-N-(2-aminophenyl)-benzamides and their analogs is described. Some of these compounds were shown to inhibit HDAC1 with IC50 values below the micromolar range, indu
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Doi:10.1134/S1070428009020055
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