Journal of Organic Chemistry p. 2721 - 2724 (1986)
Update date:2022-08-04
Topics:
Nelson, Keith A.
Mash, Eugene A.
An efficient, enantioselective preparation of (R)-muscone employing a diastereoselective Simmons-Smith cyclopropanation is described.Cyclopropanation is directed via chelation control by a homochiral ketal protecting group derived from unnatural tartaric acid.The overall yield of (R)-muscone (>95percent R) from commercially available cyclopentadecanone is 60percent over seven steps.
View MoreBAODING SINO-CHEM INDUSTRY CO.,LTD
Contact:0312-5956088
Address:NO.8 FUXING ROAD,CHINA
Contact:+86-633-8332928
Address:No.1,Huanghai Yilu.Rizhao,Shandong
Contact:+86-10-62651721
Address:29 Yongxing Road, Daxing District,Beijing China
Shanghai Dianyang Industry Co.,ltd
Contact:+86 21 6492 4669
Address:Chejing RD, Songjiang District, Shanghai, China
Zhejiang Chemicals Import & Export Corporation (ZHECHEM)
Contact:+86-571-87046953
Address:No. 37, Qingchun Road
Doi:10.1016/S0957-4166(97)00456-4
(1997)Doi:10.1002/1099-0690(200007)2000:13<2379::AID-EJOC2379>3.0.CO;2-F
(2000)Doi:10.1002/anie.201412132
(2015)Doi:10.1039/p19960001305
(1996)Doi:10.1021/jm00030a013
(1994)Doi:10.1021/ja02179a017
(1914)
