A regioselective synthesis of 3-isoprenyl-4-hydroxycoumarins

Article abstract of DOI:10.1080/00397919208019073

The dianion of ethyl 3-(2-hydroxyphenyl)-3-oxopropanoate can be regioselectively alkylated with isoprenyl bromides to give, after hydrolytic work-up, the corresponding 3-substituted-4-hydroxycoumarins.

Full text of DOI:10.1080/00397919208019073

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Synthetic Communications: An
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A Regioselective Synthesis of 3-
Isoprenyl-4-Hydroxycoumarins
G. Appendino a , G. Cravotto a , G. M. Nano a & G.
Palmisano b
a Dipartimento di Scienza e, Tecnologia del
Farmaco, Via P. Giuria 9, I-10125, Torino, Italy
b Dipartimento di Chimica Organica e Industriale,
Centro CNR per lo Studio delle Sostanze Organiche
Naturali, Via Venezian 21, I-20133, Milano, Italy
Version of record first published: 24 Sep 2006.
To cite this article: G. Appendino, G. Cravotto, G. M. Nano & G. Palmisano
(1992): A Regioselective Synthesis of 3-Isoprenyl-4-Hydroxycoumarins, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 22:15, 2205-2212
To link to this article: http://dx.doi.org/10.1080/00397919208019073
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