Journal of the Chemical Society. Perkin transactions I p. 1235 - 1238 (1993)
Update date:2022-08-05
Topics:
Beard, Andrew R.
Hazell, Sarah J.
Mann, John
Palmer, Christopher
We describe an efficient, six-stage synthesis of 2-methyl-4-deoxyisopicropodophyllotoxin, which proceeds via a Diels-Alder cycloaddition between 2-methylmaleic anhydride and the orthoquinodimethane generated by treatment of 5-<1-acetoxy-1-(3',4',5'-trimet
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Doi:10.1021/jo01288a015
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