A total synthesis of arenastatin A, an extremely potent cytotoxic depsipeptide, from the Okinawan marine sponge dysidea arenaria

DOI: 10.1248/cpb.42.2394

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2394 - 2396 (1994)

Update date:2022-07-31

Topics:

Authors:

Kobayashi

Kurosu Kurosu

Wang Wang

Kitagawa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.42.2394

An asymmetric synthesis of a cyclic depsipeptide arenastatin A (1), which was isolated from the marine sponge Dysidea arenaria and exhibited extremely potent cytotoxicity with IC₅₀ 5 pg/ml for KB cells, has been accomplished.

Full text of DOI:10.1248/cpb.42.2394

NII-Electronic Library Service

Products guided by the article

Product name:2,2-Dimethyl-propionic acid (2R,3S)-5-(tert-butyl-diphenyl-silanyloxy)-2-methyl-3-triethylsilanyloxy-pentyl ester

Cas No:1026475-30-8

R&D Labs maybe for 1026475-30-8

Hangzhou yi lu biont technology Co., LTD

Contact:+86-571-88152630

Address:Hangzhoushi HuafengRoad Yicheng3Building1001room.
Hangzhou Ledun Technology Co.,Ltd.

Contact:86-571-18767088918

Address:No.6 street,XiaSha,Hangzhou,China.
Guangxi Nanning Guangtai Agriculture Chemical Co.,Ltd

Contact:+86-771-2311266

Address:Room703,Building12, Software Park Phase II,NO.68,Keyuan Road,Nanning City,Guangxi,China
Advanced Biotech

Contact:+1-973-357-0577

Address:10 Taft Rd.
Suzhou Health Chemicals Co., Ltd.

website:http://www.healthchems.com

Contact:13776257979

Address:No. 338, Jingang Avenue,

Relevant to this article

N-phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: Structure-activity studies and demonstration of in vivo activity

Doi:10.1021/jm980072p
(1998)
Synthesis and Antiulcer Activity of 5,11-Dihydro<1>benzoxepino<3,4-b>pyridines

Doi:10.1021/jm00399a016
(1988)
Construction of an asymmetric quaternary carbon via an asymmetric aza-Claisen rearrangement and its application in the total synthesis of (+)-α-cuparenone

Doi:10.1016/j.tetasy.2012.05.016
(2012)
Gold(I)-catalyzed regio- and stereoselective 1,3-dipolar cycloaddition reactions of 1-(1-Alkynyl)cyclopropyl oximes with nitrones: A modular entry to highly substituted pyrrolo[3,4-d][1,2]oxazepines

Doi:10.1002/adsc.201200288
(2012)
A NEW ENTRY TO HOMOCHIRAL DIFLUORINATED COMPOUNDS

Doi:10.1016/S0957-4166(00)82007-8
(1991)
Design, synthesis and biological evaluation of tricyclic pyrazolo[1,5-c][1,3]benzoxazin-5(5H)-one scaffolds as selective BuChE inhibitors

Doi:10.1080/14756366.2018.1488696
(2018)

Article Doi