European Journal of Medicinal Chemistry p. 529 - 534 (1997)
Update date:2022-08-04
Topics:
Vazquez
Rosell
Pujol
Racemic (R,S)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)propionic acid (3) has been prepared from 2,3-dihydro-1,4-benzodioxin. R-(-)-Pantolactone has been used as auxiliary for the synthesis of R-3 and S-3. The anti-inflammatory properties of the new carboxylic acids are described and compared with other anti-inflammatory agents. The highest activity is exhibited by compound S-3.
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Doi:10.1016/S0040-4039(01)02023-8
(2001)Doi:10.1016/j.tetlet.2010.07.042
(2010)Doi:10.1248/cpb.41.529
(1993)Doi:10.1002/ejic.200601004
(2007)Doi:10.1080/10426509908546308
(1999)Doi:10.1007/BF02495930
(1997)
