Synthesis of 2(1H)-pyrimidinone-containing α-amino acid derivatives by chemical modification of L-glutamic acid

DOI: 10.1248/cpb.42.1514

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1514 - 1517 (1994)

Update date:2022-08-04

Topics: Synthesis Derivatives Chemical modification L-Glutamic Acid Experimental α-Amino Acid Derivatives

Authors:

Katoh Katoh

Inokawa Inokawa

Ohkanda Ohkanda

Mitsuhashi

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Article abstract of DOI:10.1248/cpb.42.1514

A commercially available L-glutamic acid γ-methyl ester was converted into the corresponding urea-containing α-amino acid via the hydrazide, the azide, and then the isocyanate. The condensation of the urea-containing α- amino acid with β-diketones under a

Full text of DOI:10.1248/cpb.42.1514

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