A synthetic approach to Benanomicin A. 2. Synthesis of the substituted 5,6-dihydrobenzo[a]naphthacenequinone

Article abstract of DOI:10.7164/antibiotics.50.755

The key intermediate tri-substituted α-tetralone (8) has been synthesized, either via tandem MICHAEL addition-DIECKMANN condensation reaction between dienolate and methyl crotonate in a low yield or via BARTON'S radical decarboxylation of diester (9) with