Avermectin-Milbemycin Studies. 4. An Expedient Two-Step Preparation of p-Hydroxybenzoates

DOI: 10.1016/S0040-4039(00)88919-4

Source and publish data:

Tetrahedron Letters p. 4419 - 4422 (1985)

Update date:2022-07-30

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Authors:

Smith, Amos B.

Kilenyi, Nicholas S.

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Article abstract of DOI:10.1016/S0040-4039(00)88919-4

Dianions derived from a variety of 1,3-diketones react with Z-ethyl-3-bromopropenoate to afford unsaturated diketoesters which upon treatment with base undergo facile cyclization-dehydration to p-hydroxybenzoates.

Full text of DOI:10.1016/S0040-4039(00)88919-4

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