
Journal of Medicinal Chemistry p. 2394 - 2400 (1994)
Update date:2022-08-04
Topics:
Picard
Bousley
Lee
Hamelehle
Krause
Minton
Sliskovic
Stanfield
Five series of compounds (4-9) derived from N-(chlorocarbonyl) isocyanate have been synthesized and evaluated for their ability to inhibit the enzyme acyl-CoA:cholesterol O-acyltransferase and lower plasma cholesterol levels in cholesterol-fed rats. Struc
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