Journal of the Chemical Society. Chemical communications p. 1808 - 1809 (1985)
Update date:2022-08-03
Topics:
Baldwin, Jack E.
Abraham, Edward P.
Burge, Geoffrey L.
Ting, Hong-Hoi
The enzyme isopenicillin N synthetase is able to convert directly the dipeptides, phenoxyacetylcysteinylvaline and phenylacetylcysteinylvaline into penicillin V and G respectively; these are however very slow compared with substrates of the α-aminoadipoyl or adipoylcysteinylvaline type.
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