4,5-Disubstituted primaquine analogues as potential antimalarial agents

DOI: 10.1021/jm00159a042

Source and publish data:

Journal of Medicinal Chemistry p. 1796 - 1798 (1986)

Update date:2022-08-04

Topics:

Authors:

Carroll Carroll

Berrang Berrang

Linn Linn

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Article abstract of DOI:10.1021/jm00159a042

Three 4,5-disubstituted primaquine analogues were synthesized and evaluated for radical curative activity against Plasmodium cynomolgi in rhesus monkeys. One of the compounds showed moderate activity; however, none of the three compounds were as active as

Full text of DOI:10.1021/jm00159a042

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