STRUCTURAL AND STEREOCHEMICAL STUDIES ON MARINE NORTERPENE CYCLIC PEROXIDES

Article abstract of DOI:10.1016/S0040-4020(01)96691-8

Isolation of a new norditerpene cyclic peroxide (12) and three new norsesterpene cyclic peroxides (1, 2, 26) has permitted a detailed study of the stereostructures of this unusual class of marine natural product.A procedure for assigning relative and absolute stereochemistry about the peroxy moiety is outlined.An absolute stereostructure for muqubilin (11) and a revision of the previously assigned absolute stereochemistry of the sigmosceptrellins (5-10) is proposed, the latter based on the Horeau procedure.