Tetrahedron p. 3091 - 3094 (1985)
Update date:2022-07-31
Topics:
Florio, Saverio
Ingrosso, Giovanni
Sgarra, Riccardo
2-Alkylbenzoxazoles 1 undergo clean Claisen-type self-condensation upon treatment with n-BuMgBr and quenching with aqueous NH4Cl to give 5.In contrast, quenching of the reaction with aqueous HCl furnishes quite good yields of the benzoxazolylalkyl alkyl ketones 8.
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