New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents

Article abstract of DOI:10.1021/jm00080a018

Novel neplanocin A analogues modified at the 6'-position, i.e., 6'-deoxy analogues (2, 3, 6, 9, 20), 6'-O-methylneplanocin A (15), and 6'-C- methylneplanocin A's (22a and 22b) have been synthesized and evaluated for their antiviral activity in a wide vari