Journal of Medicinal Chemistry p. 1229 - 1239 (1987)
Update date:2022-08-03
Topics: Design Experimental
Evans, B. E.
Rittle, K. E.
Bock, M. G.
DiPardo, R. M.
Freidinger, R. M.
et al.
A series of 3-substituted-5-phenyl-1,4-benzodiazepines, nonpeptidal antagonists of the peptide hormone cholecystokinin (CCK), have been synthesized.Designed on the basis of facts regarding CCK, its natural-product antagonist asperlicin (3), and the antian
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