Synthesis of Peptide-Derived Amino Alcohols. 1. Potential Transition-State Inhibitors of Angiotensin Converting Enzyme

Article abstract of DOI:10.1021/jo00365a047

Synthetic methods and protection schemes were developed for "peptidyl amino alcohols" in which a novel "amino alcohol" design element is introduced into a peptide backbone to produce a new class of proteolytic enzyme inhibitors.