Synthesis of Peptide-Derived Amino Alcohols. 1. Potential Transition-State Inhibitors of Angiotensin Converting Enzyme

DOI: 10.1021/jo00365a047

Source and publish data:

Journal of Organic Chemistry p. 3073 - 3075 (1986)

Update date:2022-07-30

Topics:

Authors:

Godfrey, J. D.

Gordon, E. M.

Langen, D. Von

Engebrecht, J.

Pluscec, Jelka

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Article abstract of DOI:10.1021/jo00365a047

Synthetic methods and protection schemes were developed for "peptidyl amino alcohols" in which a novel "amino alcohol" design element is introduced into a peptide backbone to produce a new class of proteolytic enzyme inhibitors.

Full text of DOI:10.1021/jo00365a047

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