Journal of Medicinal Chemistry p. 1941 - 1945 (1986)
Update date:2022-09-26
Topics: Synthesis Potency Antagonists Analogues Water Solubility Cholecystokinin
Bock, Mark G.
DiPardo, Robert M.
Rittle, Kenneth E.
Evans, Ben E.
Freidinger, Roger M.
et al.
Seventeen analogues of the selective, competitive cholecystokinin (CCK) antagonist asperlicin 1 were prepared.These compounds were tested as inhibitors of the binding of <125I>CCK to rat pancreas and guinea pig brain receptors.Compounds 4, 7, and 8 were m
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(1986)
