Enantioselective organocatalytic Michael addition of malonates to α,β-unsaturated aldehydes in water

DOI: 10.1016/j.tetlet.2008.03.051

Source and publish data:

Tetrahedron Letters p. 3075 - 3077 (2008)

Update date:2022-08-03

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Authors:

Ma, Anqi

Zhu, Shaolin

Ma, Dawei

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Article abstract of DOI:10.1016/j.tetlet.2008.03.051

The Michael addition of malonates to α,β-unsaturated aldehydes catalyzed by O-TMS protected diphenylprolinols and acetic acid in water occurs at 0 °C to rt. In most cases, the reaction runs to completion in less than 24 h. A wide range of aldehydes includ

Full text of DOI:10.1016/j.tetlet.2008.03.051

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