Asymmetric Catalysis, Part 91: Enantioselective Monophenylation of cis-1,2-Cyclopentanediol with Triphenylbismuth Diacetate and Chiral Copper(II) Complexes as Catalysts

Article abstract of DOI:10.1007/BF00811078

The monophenylation of cis-1,2-cyclopentanediol with triphenylbismuth diacetate in the presence of chiral Cu(II) complexes as catalysts gave cis-2-hydroxy-1-phenoxy-cyclopentane with enantiomeric excesses up to 38percent.The optically active ligands used were triamine derivatives of 2,6-bis(aminomethyl)pyridine and diamine derivatives of 2-(aminomethyl)pyridine.Selectivity in the monophenylation occurred only in the presence of the latter as auxiliary ligands. - Keywords.Enantioselective catalysis; Chiral Cu(II) complexes; Monophenylation; Triphenylbismuth diacetate; cis-1,2-Cyclopentanediol.