Synthesis and Antitumor Activity of Quaternary Ellipticine Glycosides, a Series of Novel and Highly Active Antitumor Agents

DOI: 10.1021/jm00402a007

Source and publish data:

Journal of Medicinal Chemistry p. 1295 - 1305 (1988)

Update date:2022-08-02

Topics:

Authors:

Honda, Tadashi

Kato, Mika

Inoue, Minako

Shimamoto, Tetsuo

Shima, Keiyuu

et al. et al.

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Article abstract of DOI:10.1021/jm00402a007

A series of ellipticine glycosides <2-N-glycosyl quaternary pyridinium salts of three ellipticines: ellipticine (1), 9-methoxyellipticine (2), and 9-hydroxyellipticine (4)> were stereoselectively synthesized in good yields by an improved condensation reac

Full text of DOI:10.1021/jm00402a007

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