Mechanism of the one-pot synthesis of 3-amino-3-(2-nitrophenyl)propionic acid

DOI: 10.1002/ardp.19863190603

Source and publish data:

Archiv der Pharmazie p. 488 - 492 (1986)

Update date:2022-09-26

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Authors:

Oelschlager

Ogorka Ogorka

Kolbeck Kolbeck

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Article abstract of DOI:10.1002/ardp.19863190603

The one-pot synthesis of 3-amino-3-(2-nitrophenyl)propionic acid (1) from o-nitrobenzaldehyde, malonic acid in ammonium acetate/acetic acid occurs in 3 steps: condensation, addition and decarboxylation. Side reactions were investigated.

Full text of DOI:10.1002/ardp.19863190603

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