STERIC AND ELECTRONIC LIMITATIONS OF THE SRN1 REACTION BETWEEN p-NITROBENZYLIC SUBSTRATES AND TERTIARY CARBANIONS

Article abstract of DOI:10.1016/S0040-4039(00)98673-8

The S_RN1 reaction between sterically hindered p-nitrobenzylic substrates and tertiary carbanions gives C-alkylated products whose yields depend on the steric bulk of both the benzylic substrate and the carbanion, and on the nature of the groups in the carbanion.