PARTICIPATION OF PERI-HYDROXYL GROUP IN THE TRIFLUOROACETOLYSIS OF NAPHTHALENESULFONAMIDES

DOI: 10.1016/S0040-4039(00)95128-1

Source and publish data:

Tetrahedron Letters p. 6071 - 6074 (1985)

Update date:2022-08-05

Topics:

Authors:

Mazaleyrat, Jean-Paul

Wakselman, Michel

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Article abstract of DOI:10.1016/S0040-4039(00)95128-1

Trifluoroacetolysis of N-alkyl-8-hydroxy-naphthalenesulfonamides generally leads to the corresponding amines and naphthosultones.A model experiment shows that this reaction may be used in a two-step cleavage of sulfonamide protecting groups.

Full text of DOI:10.1016/S0040-4039(00)95128-1

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