AN APPROACH TO THE SYNTHESIS OF α-L-FUCOPYRANOSYL PHOSPHORIC MONO- AND DIESTERS VIA PHOSPHITE INTERMEDIATES

Article abstract of DOI:10.1016/S0040-4039(00)84219-7

The reagent chloro-β-cyanoethyl-N,N-diisopropylamino-phosphoramidite reacts smoothly with the anomeric hydroxyl group of a properly protected (benzyl) α-L-fucopyranose to afford a relatively stable phosphite intermediate in high yield.The latter can easil