Synthesis and Antitumor Activity of Certain 3-β-D-Ribofuranosyl-1,2,4-triazolo-1,2,4-triazines Related to Formycin Prepared via Ring Closure of a 1,2,4-Triazine Precursor

DOI: 10.1021/jm00161a017

Source and publish data:

Journal of Medicinal Chemistry p. 2231 - 2235 (1986)

Update date:2022-07-29

Topics:

Authors:

Ramasamy, Kandasamy

Ugarkar, Bheemarao G.

McKernan, Patricia A.

Robins, Roland K.

Revankar, Ganapathi R.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00161a017

Several 3-β-D-ribofuranosyl-1,2,4-triazolo<3,4-f>-1,2,4-triazines related to formycin were prepared and tested for their antitumor activity in cell culture.Dehydrative coupling of 3-amino-6-hydrazino-1,2,4-triazin-5(4H)-one (5) with 3,4,6-tri-O-benzoyl-2,

Full text of DOI:10.1021/jm00161a017

Products guided by the article

Product name:C₃₀H₂₆N₆O₉

Cas No:103959-81-5

R&D Labs maybe for 103959-81-5

Zhejiang Newfine Industry Co.,Ltd.

Contact:+86-573-82262042

Address:No.225,Dongqing Road, garoms@163.com
Airsea(Taizhou) Pharmaceutical Limited(expird)

Contact:+86-576-88057622

Address:Dubei, Duqiao, Linhai, Taizhou, Zhejiang, China Zip: 317016
Zibo Linzi Darong Fine Chemical Co., Ltd(expird)

Contact:86-532-67773200; 15689126900

Address:Qidu town,Linzi district,Zibo city,Shandong province,China
Shaanxi King Stone Enterprise Company Limited

Contact:86-29-88353805,13609285751

Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
Radiant Pharma & Tech Company

Contact:+86-511-88790000

Address:338 North Yushan Rd, Zhenjiang, Jiangsu 212016

Relevant to this article

Chlorohydroaspyrones A and B, antibacterial aspyrone derivatives from the marine-derived fungus Exophiala sp.

Doi:10.1021/np800107c
(2008)
Scalable synthesis of enantiomerically pure cis-1,2-cyclohexanediamine derivatives and conformationally rigid 7-azabicyclo[2.2.1]heptan-2-amines

Doi:10.1002/ejoc.201300253
(2013)
Synthesis, nano-scale assembly, and in vivo anti-thrombotic activity of novel short peptides containing l-Arg and l-Asp or l-Glu

Doi:10.1016/j.bmc.2008.04.064
(2008)
Urotropin synthesis of 3,5-di-tert-butylsalicylic acid derivatives

Doi:10.1134/S1070428007100132
(2007)
Combinatorial and automated synthesis of phosphodiester galactosyl cluster on solid support by click chemistry assisted by microwaves

Doi:10.1021/jo8009837
(2008)
Ferrocene-based small molecules for dual-channel sensing of heavy- and transition-metal cations

Doi:10.1021/jo800709v
(2008)

Article Doi