Design, synthesis of 8-alkoxy-5,6-dihydro-[1,2,4]triazino[4,3-a]quinolin-1-ones with anticonvulsant activity

DOI: 10.1016/j.ejmech.2008.09.003

Source and publish data:

European Journal of Medicinal Chemistry p. 1265 - 1270 (2009)

Update date:2022-07-31

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Authors:

Sun, Xian-Yu

Zhang, Lei

Wei, Cheng-Xi

Piao, Hu-Ri

Quan, Zhe-Shan

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Article abstract of DOI:10.1016/j.ejmech.2008.09.003

A new series of 8-alkoxy-5,6-dihydro-[1,2,4]triazino[4,3-a]quinolin-1-one derivatives were synthesized. Their anticonvulsant activities were evaluated by the maximal electroshock (MES) test, and their neurotoxicities were evaluated by the rotarod neurotox

Full text of DOI:10.1016/j.ejmech.2008.09.003

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