Tetrahedron Letters p. 6873 - 6875 (2008)
Update date:2022-08-05
Topics:
Sakai, Norio
Fujii, Kohji
Konakahara, Takeo
We have developed a simple and practical procedure for a direct reductive conversion from a variety of tertiary amides to the corresponding tertiary amines using an InBr3/Et3SiH reducing system. This reducing system can be applied to the reduction of a secondary amide and provides a more efficient alternative to conventional methods that use aluminum and boron hydrides.
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