Journal of Organic Chemistry p. 4023 - 4028 (1986)
Update date:2022-08-05
Topics:
Parker, Kathlyn A.
Farmar, James G.
The stereoselective synthesis of dl-biflora-4,10(19),15-triene (1), a bicyclic diterpene component of the defense secretion of termite soldiers (Cubitermes umbratus), makes use of the regioselective Ireland-Claisen rearrangement of the Z-enolates of esters of 2,5-disubstituted 1,4-dien-3-ols.The synthetic scheme links the dienol Ireland-Claisen rearrangement with an intramolecular Diels-Alder closure; this strategy allows introduction of the four contiguous chiral centers with the desired relative stereochemistry.
View MoreDalian Synco Chemical Co., Ltd.
Contact:+86-411-83635150
Address:Rm 1004, 24, Tangshan Street, Dalian
website:http://www.shochem.com
Contact:021-50800795
Address:No.1043, Halei Rd, Zhangjiang Hi-Tech Park, Shanghai, Postcode 201203, China
Hangzhou Dingyan Chem Co., Ltd
website:http://www.dingyanchem.com
Contact:86-571-87157530
Address:RM.1118,NO.1 Building, Baiyun Tower,Jianggan Area, Hangzhou city, China,310004
Shanghai Xinda Pharmaceuticals Co., Ltd.
Contact:86-21-33692333-8008
Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
Xiamen Goodhealth Pharmchem Co., Ltd.
Contact:0086-592-2097683
Address:404R No.2 54# Minzu Rd., Xiamen, China
Doi:10.1016/j.bmcl.2008.04.072
(2008)Doi:10.1016/j.bmcl.2008.04.056
(2008)Doi:10.1016/j.tet.2008.04.067
(2008)Doi:10.1107/S0108270107034786
(2007)Doi:10.1021/ol801424m
(2008)Doi:10.1039/b718171j
(2008)
