Archiv der Pharmazie p. 720 - 727 (1986)
Update date:2022-08-03
Topics:
Reisch, Johannes
Bathe, Andreas
Salehi-Artimani, Reza A.
Reaction of 4-hydroxyquinolin-2-one (4) with 3-chloro-3-methylbut-1-yne by phase-transfer catalysis affords flindersine (3) and 2,3-dihydro-3,3-dimethyl-2-methylenefuro<3,2-c>quinolin-4-one (5), whereas indolin-2-one (4g) yields N-(1,1-dimethylprop-2-yn-1-yl)indolin-2-one (19).The reaction mechanism is discussed and studied by varying the reaction conditions.
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Doi:10.1134/S1070363217070143
(2017)Doi:10.3987/R-1986-03-0777
(1986)Doi:10.1016/j.tetlet.2008.05.077
(2008)Doi:10.1039/d0dt02557g
(2020)Doi:10.1021/ol8012588
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(2008)
