Synthesis and Structure-Activity Studies of N,N'-Diarylguanidine Derivatives. N-(1-Naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine: A New, Selective Noncompetitive NMDA Receptor Antagonist

DOI: 10.1021/jm00028a009

Source and publish data:

Journal of Medicinal Chemistry p. 260 - 267 (1994)

Update date:2022-08-05

Topics:

Authors:

Reddy, N. Laxma

Hu, Lain-Yen

Cotter, Ronald E.

Fischer, James B.

Wong, Wen Jee

et al. et al.

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Article abstract of DOI:10.1021/jm00028a009

Diarylguanidines, acting as NMDA receptor ion channel site ligands, represent a new class of potential neuroprotective drugs.Several diarylguanidines structurally related to N,N'-di-o-tolylguanidine (DTG), a known selective ? receptor ligand, were synthes

Full text of DOI:10.1021/jm00028a009

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