Synthesis and Structure-Activity Studies of N,N'-Diarylguanidine Derivatives. N-(1-Naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine: A New, Selective Noncompetitive NMDA Receptor Antagonist

DOI: 10.1021/jm00028a009

Source and publish data:

Journal of Medicinal Chemistry p. 260 - 267 (1994)

Update date:2022-08-05

Topics:

Authors:

Reddy, N. Laxma

Hu, Lain-Yen

Cotter, Ronald E.

Fischer, James B.

Wong, Wen Jee

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00028a009

Diarylguanidines, acting as NMDA receptor ion channel site ligands, represent a new class of potential neuroprotective drugs.Several diarylguanidines structurally related to N,N'-di-o-tolylguanidine (DTG), a known selective ? receptor ligand, were synthes

Full text of DOI:10.1021/jm00028a009

Products guided by the article

Product name:Guanidine, N,N'-bis([1,1'-biphenyl]-2-yl)-

Cas No:104919-90-6

R&D Labs maybe for 104919-90-6

HangZhou HuaYe Chemical Technology Co.,Ltd

Contact:+86-13505815007

Address:hangzhou
Nanjing Chemzam Pharmtech Co., Ltd.

Contact:+86-25-86462165,+86-13915979898

Address:C5-1，6 Maiyue Road，Maigaoqiao，Nanjing，Jiangsu，China
Okeanos Tech.Co.,LTD

Contact:+86-10-62651721

Address:29 Yongxing Road, Daxing District,Beijing China
SICHUAN ZHONGBANG NEW MATERIAL CO., LTD

website:http://www.zhongbangst.com

Contact:86-830-2585019

Address:sichuan,china
Anhui Eapearl Chemical Co., Ltd.

Contact:86-562-5858458

Address:358 South Huaihe Road

Relevant to this article

SYNTHESIS OF 5-OXOINDENO<1,2.b>PYRIDINIUM SALTS

Doi:10.1007/BF00515428
(1986)
Pd(OAc)₂-catalyzed regioselective arylation of indoles with arylsiloxane in acidic medium

Doi:10.1021/ol101147b
(2010)
BIS(ARENE)METAL COMPOUNDS I. NUCLEOPHILIC SUBSTITUTION OF BIS(η⁶-CHLOROBENZOTRIFLUORIDE)CHROMIUM(0) WITH THIOPHENOXIDE

Doi:10.1016/0022-328X(86)84037-2
(1986)
Bicyclic diols and related derivatives as catalysts for the asymmetric diethylzinc addition to benzaldehyde

Doi:10.1016/j.tetasy.2008.05.024
(2008)
Highly stereoselective construction of 4,6-cis-substituted quinolizidine ring core: An application to enantioselective total synthesis of the marine alkaloid clavepictines A, B and pictamine

Doi:10.1016/S0040-4020(99)00996-5
(1999)
In vitro antibacterial activity of CE-156811, a novel analog derived from hygromycin A

Doi:10.1128/AAC.01326-07
(2008)

Article Doi