Synthesis and antibacterial activity of 2-[(methoxycarbonyl)methylene]cephalosporins

DOI: 10.1021/jm00375a026

Source and publish data:

Journal of Medicinal Chemistry p. 1225 - 1229 (1984)

Update date:2022-08-02

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Authors:

Kim Kim

Misco Misco

Haynes Haynes

McGregor

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Article abstract of DOI:10.1021/jm00375a026

The synthesis and in vitro activities of a series of 2-[(methoxycarbonyl)methylene]-3-cephem-4-carboxylic acids with methyl or acetoxymethyl at the 3-position are described. The key step in the synthesis includes the stereospecific formation of the 2-[(Z)

Full text of DOI:10.1021/jm00375a026

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