Synthesis and Evaluation of 3-Dehydroquinate Synthase Transition State Analogues

DOI: 10.1021/jo00104a013

Source and publish data:

Journal of Organic Chemistry p. 7596 - 7601 (1994)

Update date:2022-07-29

Topics: Synthesis Evaluation Analogues Transition state

Authors:

Montchamp, Jean-Luc

Frost, J. W.

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Article abstract of DOI:10.1021/jo00104a013

Analogues have been synthesized of a six-membered, cyclic transition state likely involved in elimination of inorganic phosphate from an enzyme-bound, reactive intermediate formed during 3-dehydroquinate (DHQ) synthase catalysis.A spirocyclic carbaphospho

Full text of DOI:10.1021/jo00104a013

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