Journal of Organic Chemistry p. 5252 - 5258 (1986)
Update date:2022-09-26
Topics:
Johansson, Anette M.
Mellin, Charlotta
Hacksell, Uli
Two efficient syntheses of 5-methoxy- and 8-methoxy-3-methyl-2-tetralone and the synthesis of the 7-methoxy isomer via a different route are described.Also reported is the synthesis of 8-methoxy-3,3-dimethyl-2-tetralone.The regioselectivity of lithium carbanion formation in 1,6-, 1,7-, and 2,7-dihydroxynaphthalene is discussed.The latter compound undergoes dimetalation more easily than the other isomers.
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