SYNTHESIS OF LIPOXIN B

DOI: 10.1016/S0040-4039(00)84105-2

Source and publish data:

Tetrahedron Letters p. 803 - 806 (1986)

Update date:2022-08-04

Topics:

Authors:

Morris, Joel

Wishka, Donn G.

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Article abstract of DOI:10.1016/S0040-4039(00)84105-2

The synthesis of four isomers of 5,14,15-triHETE is reported.The key step is the coupling of acetylene 11 (or 19) with epoxide 7 to afford alcohol 12 (or 20).Natural lipoxin B is found to correspond to a mixture of 14R-8-cis-1 14R-8-trans-3 and 14S-8-tran

Full text of DOI:10.1016/S0040-4039(00)84105-2

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