5-Quinone Derivatives of 2'-Deoxyuridine 5''-Phosphate: Inhibition and Inactivation of Thymidylate Synthase, Antitumor Cell, and Antiviral Studies

Article abstract of DOI:10.1021/jm00385a026

Both photochemical aromatic substitution and palladium(0)-catalyzed biaryl coupling reactions have been employed in the synthesis of 5-substituted 2'-deoxyuridines.The former procedure was useful in the preparation of the 3,4-dimethyl-2,5-dimethoxyphenyl