DESIGN AND SYNTHESIS OF DNA INTERCALATING CROWN ETHER MOLECULES

DOI: 10.1016/S0040-4039(00)83924-6

Source and publish data:

Tetrahedron Letters p. 3 - 6 (1986)

Update date:2022-07-30

Topics:

Authors:

Basak, A.

Dugas, H.

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Article abstract of DOI:10.1016/S0040-4039(00)83924-6

We describe the synthesis of a series of novel mono- and bis-intercalant crown ethers 1 and 2, having either a methidium or a psoralen function covalently attached to the macrocyclic ring with well-defined stereo chemistry.Their binding efficiency to DNA duplex has been evaluated.

Full text of DOI:10.1016/S0040-4039(00)83924-6

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