Synthesis and 3'-Substituent Effects of Some 7α-Methoxy-1-oxacephems on Antibacterial Activity and Alkaline Hydrolysis Rates

DOI: 10.1021/jm00386a013

Source and publish data:

Journal of Medicinal Chemistry p. 514 - 522 (1987)

Update date:2022-08-05

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Authors:

Narisada, Masayuki

Nishikawa, Junko

Watanabe, Fumihiko

Terui, Yoshihiro

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Article abstract of DOI:10.1021/jm00386a013

Relationships between intrinsic antibacterial activity and β-lactam chemical reactivity of 7β-(phenylacetamido)-7α-methoxy-1-oxacephems with various 3'-substituents (1-9) were studied in order to clarify the effect of the 3'-substituent on the antibacteri

Full text of DOI:10.1021/jm00386a013

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