Synthesis and 3'-Substituent Effects of Some 7α-Methoxy-1-oxacephems on Antibacterial Activity and Alkaline Hydrolysis Rates

DOI: 10.1021/jm00386a013

Source and publish data:

Journal of Medicinal Chemistry p. 514 - 522 (1987)

Update date:2022-08-05

Topics:

Authors:

Narisada, Masayuki

Nishikawa, Junko

Watanabe, Fumihiko

Terui, Yoshihiro

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00386a013

Relationships between intrinsic antibacterial activity and β-lactam chemical reactivity of 7β-(phenylacetamido)-7α-methoxy-1-oxacephems with various 3'-substituents (1-9) were studied in order to clarify the effect of the 3'-substituent on the antibacteri

Full text of DOI:10.1021/jm00386a013

Products guided by the article

Product name:(2R,6R,7R)-7-Benzoylamino-7-methoxy-3-methylene-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid benzhydryl ester

Cas No:106162-88-3

R&D Labs maybe for 106162-88-3

Tianjin Anda North Industrial & Business Co.Ltd.

Contact:86-22-24999306

Address:No.11 Erwei Road,Dongli Development Area,Tianjin,China
Nanjing Ruizhi Industry & Technologh Co.，Ltd.

Contact:+86-25-86808110

Address:441-4-A5,NO.12 Longzang Avenue,Yuhuatai District,210039,Nanjing
SJZ Chenghui Chemical Co., Ltd.

Contact:86-311-87713916

Address:no.368 youyi north avenue
Du-Hope International Group

website:http://www.np-chem.com

Contact:0086-25-52346877

Address:199, Jian Ye Road, Nanjing, China
Dalian Join King Biochemical Tech. Co., Ltd.

Contact:0411 39216206

Address:814 First State Blvd

Relevant to this article

Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives

Doi:10.1016/j.bmc.2008.05.072
(2008)
Novel purine and pyrazolo[3,4-d]pyrimidine inhibitors of PI3 kinase-α: Hit to lead studies

Doi:10.1016/j.bmcl.2009.11.051
(2010)
A novel 3-substituted benzazepinone growth hormone secretagogue (L- 692,429)

Doi:10.1021/jm00033a006
(1994)
UN UNUSUAL PRODUCT OF THE REACTION OF l-PHENYL-3-(3,4-DIMETHOXYPHENYL)-3-(2-OXOCYCLOHEXYL)-1-PROPANONE WITH HYDROGEN SULFIDE AND ACIDS: 2α-PHENYL-2,4-ortho-(14,15-DIMETHOXYBENZO)-cis-1-THIADECALIN

Doi:10.1007/BF00519935
(1986)
A convenient synthesis of 4-(phenylsulfonylthio)-2-azetidinones

Doi:10.1246/bcsj.64.1416
(1991)
Synthesis of multivalent β-lactosyl clusters as potential tumor metastasis inhibitors

Doi:10.1016/0008-6215(93)80071-L
(1993)

Article Doi