Novel Transformations Leading to 3-Benzylindolizidin-2-ones

DOI: 10.1021/jo00378a012

Source and publish data:

Journal of Organic Chemistry p. 226 - 235 (1987)

Update date:2022-08-03

Topics:

Authors:

Norman, Mark H.

Heathcock, Clayton H.

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Article abstract of DOI:10.1021/jo00378a012

Several derivatives of keto amide 10 have been prepared and their cyclization reactions investigated.Oxime 11 and 2,4-dinitrophenylhydrazone 12 cyclize to give isoxazolidine 16 and pyrazolidine 17, respectively, under acidic conditions (Scheme II).Oxime 1

Full text of DOI:10.1021/jo00378a012

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