Synthesis of 6,7-dimethoxypyrimido[4,5-b]-indoles as potential antihypertensive agents

Article abstract of DOI:10.1002/jhet.5570250607

Using ethyl 5,7-dimethoxy-2-amino-3-indolecarboxylate as a synthon, routes are described for the synthesis of the title compounds bearing alkylamino moieties in the 2 and 4-positions. Some of the compounds displayed antihypertensive activity.