2-pyrimidine Derivatives: New Bronchosecretolytic Agents

DOI: 10.1021/jm00386a018

Source and publish data:

Journal of Medicinal Chemistry p. 547 - 551 (1987)

Update date:2022-08-05

Topics:

Authors:

Schickaneder, Helmut

Engler, Heidrun

Szelenyi, Istvan

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Article abstract of DOI:10.1021/jm00386a018

2-<(3-Pyridinylmethyl)thio>pyrimidine derivatives (1a-n) promote the excretion of phenol red into the mouse trachea, indicating an increased tracheobronchial secretion.Furthermore, 2-<(3-pyridinylmethyl)thio>pyrimidine (1a) (tasuldine) produces greater ex

Full text of DOI:10.1021/jm00386a018

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