Total Synthesis of Amphoteronolide B and Amphotericin B. 1. Strategy and Stereocontrolled Construction of Key Building Blocks

DOI: 10.1021/ja00222a028

Source and publish data:

Journal of the American Chemical Society p. 4672 - 4685 (1988)

Update date:2022-08-05

Topics:

Authors:

Nicolaou, K. C.

Daines, R. A.

Uenishi, J.

Li, W. S.

Papahatjis, D. P.

Chakraborty, T. K.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00222a028

The retrosynthetic analysis and strategy for the total synthesis of amphotericin B (1) and amphoteronolide B (2) is discussed.Focusing on subtle and repeated structural units, a retrosynthetic scheme was constructed that led to the recognition of readily

Full text of DOI:10.1021/ja00222a028

Products guided by the article

Product name:(4R,5S)-3-<2,4-dideoxy-2,4-dimethyl-5,6-O-(methylethylidene)-L-altronoyl>-4-methyl-5-phenyl-2-oxazolidinone

Cas No:106799-08-0

R&D Labs maybe for 106799-08-0

Zhengzhou Xinlian Chemical Tech Co. ,Ltd

Contact:0371-65771781 021-52042910

Address:H Part, Building I, No. 700 Gonglu Road, Pudong New Area, Shanghai
Wuhan Fortuna Chemical Co.,Ltd

website:http://www.fortunachem.com

Contact:86-27-59207850

Address:Add: Room 2015, No.2 Building, Kaixin Mansion No.107 Jinqiao Avenue, Wuhan, China
Lishui Nanming Chemical Co., Ltd(expird)

Contact:+86-0578-2134101，2697830

Address:No.19 Tongji Road Shuige Industrial zone
Shanghai AngewChem Co., Ltd.

website:http://www.angewchem.com

Contact:+86-18917157435

Address:No. 3377, Kang Xin Road, Pudong New Area, Shanghai
Zhejiang Quzhou Jiancheng Silicone Co., Ltd.(Shanghai Jiancheng Industial and Trade Co, Ltd)

Contact:18957018777 +86-570-3888777

Address:The company production base address： Quzhou City, Zhejiang Province high-tech industrial park Nianhua Road 37

Relevant to this article

The aggregation of the merocyanine dyes, depending of the type of the counterions

Doi:10.1016/j.saa.2007.10.017
(2008)
7-Phosphanorbornene Derivatives as Precursors of Esters and Amides of Two-co-ordinate Thiophosphenous O-Acid

Doi:10.1039/c39860000844
(1986)
Highly para-Selective C?H Alkylation of Benzene Derivatives with 2,2,2-Trifluoroethyl α-Aryl-α-Diazoesters

Doi:10.1002/anie.201611809
(2017)
Enantiopure quaternary α-trifluoromethyl-α-alkoxyaldehydes from L-tartaric acid derived ketoamides

Doi:10.1021/jo8013403
(2008)
Total synthesis of the resorcylic lactone-based kinase inhibitor L-783277

Doi:10.1055/s-2008-1078406
(2008)
OXIDATION OF AROMATIC AMINES WITH CHROMYL CHLORIDE - I OXYDATION OF AROMATIC PRIMARY AMINES

Doi:10.1016/S0040-4020(01)87565-7
(1986)

Article Doi