Structure-Activity Relationship in PAF-acether. 3. Hydrophobic Contribution to Agonistic Activity

DOI: 10.1021/jm00388a008

Source and publish data:

Journal of Medicinal Chemistry p. 792 - 797 (1987)

Update date:2022-08-05

Topics:

Authors:

Godfroid, Jean-Jacques

Broquet, Colette

Jouquey, Simone

Lebbar, Mariya

Heymans, Francoise

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00388a008

The synthesis of some selected PAF-acether homologues with an alkoxy-chain length from C1 to C20 in position 1 is described.All agonist activities are closely correlated among themselves and with the calculated fatty-chain hydrophobicity.After a discussio

Full text of DOI:10.1021/jm00388a008

Products guided by the article

Product name:1-Decyloxy-3-trityloxy-propan-2-ol

Cas No:106881-89-4

R&D Labs maybe for 106881-89-4

Shandong Wanda Organosilicon New Material Co., Ltd

Contact:+86-21-54177116;54302881

Address:R1318 Greenland No. 3 Lane 58 Xinjian East Rd., Minhang
Chongqing Werlchem Fine Chemical Co. Ltd

Contact:+86-23-67521957

Address:NO.15,Fortune Road,Yubei District,401121,Chongqing,China
Nanjing Legend Pharmaceutical & Chemical Co., Ltd.

Contact:+86-25-83767696

Address:14-7 Zhongshan Lu Guluo District, Nanjing
Hubei Onward Bio-Development Co., Ltd.

Contact:+86-718-8417012

Address:No.517,Shizhou Avenue,Enshi City,Hubei Province,China,445002
Chengdu King-tiger Pharm-chem. Tech. Co., Ltd

Contact:028-85317716

Address:Tianfu Life Science Park, No. 88 South Keyuan Road, Gaoxin District, Chengdu City, Sichuan Province, PRC.

Relevant to this article

CHEMISTRY OF A NEW ANTIBIOTIC: LACTIVICIN

Doi:10.1016/S0040-4020(01)90098-5
(1988)
Bakers' Yeast Mediated Synthesis of 4-Deoxy-D-lyxo-hexopyranose (4-Deoxy-D-mannose)

Doi:10.1021/jo00386a034
(1987)
Functionalized azobenzenes through cross-coupling with organotrifluoroborates

Doi:10.1016/j.tetlet.2006.12.043
(2007)
REACTION D'OXIMATION DES CETONES IV. CONSTANTES D'EQUILIBRE DE FORMATION DES CARBINOLAMINES INTERMEDIAIRES: DETERMINATION ET EFFETS DE STRUCTURE

Doi:10.1016/S0040-4020(01)90551-4
(1986)
Enantioselective Suzuki cross-couplings of unactivated 1-fluoro-1-haloalkanes: Synthesis of chiral β-, γ-, δ-, and ε-fluoroalkanes

Doi:10.1021/jacs.5b00473
(2015)
Cationic methyl complexes of the rare-earth metals: An experimental and computational study on synthesis, structure, and reactivity

Doi:10.1021/ic801259n
(2008)

Article Doi